A decision analytic dynamic Markov model on the US population aged 12 years or older was used to project the number of fatal overdoses caused by any opioid between 2020 – 2029 and project the number of deaths that can be averted by prescribing restrictions, naloxone distribution, and expansion of MAT interventions. Based on data taken from 2010-2018 National Survey on Drug Use and Health, Centers for Disease Control and Prevention, National Health and Nutrition Examination Survey, the US Census, and the National Epidemiologic Survey on Alcohol and Related Conditions- III, the status quo, the...