High-dose buprenorphine induction in the emergency department for treatment of opioid use disorder

In response to the rising efficacy of the illicit opioid drug supply and often observed delays in access to follow-up therapy, emergency departments (EDs) occasionally utilize a high-dose buprenorphine induction method for the treatment of opioid use disorder (OUD). The objective of this study is to investigate the safety and tolerability of high-dose (>12 mg) buprenorphine induction for patients with OUD presenting to an ED.
Data were manually extracted from electronic health records for all ED patients with OUD treated with buprenorphine at a single, urban, safety-net hospital in Oakland...