Alcohol policies and alcohol-attributable cancer mortality in U.S. States

Source:

Alattas, M., Ross, C. S., Henehan, E. R., & Naimi, T. S. (2020). Alcohol policies and alcohol-attributable cancer mortality in US States. Chemico-biological interactions, 315, 108885.

Abstract

Background

Although more restrictive alcohol control policies (e.g., higher alcohol taxes) are related to lower levels of alcohol consumption, little is known about the relationship between alcohol policies and rates of alcohol-attributable cancer.

Methods

State alcohol policy restrictiveness, as measured by a validated policy scale, were related to state rates of six alcohol attributable cancers in the U.S. from 2006 to 2010 in a lagged, cross-sectional linear regression that controlled for a variety of state-level factors. Cancer mortality rates were from the Center for Disease Control and Prevention's Alcohol-Related Disease Impact application, which uses population-attributable fraction methodology to calculate mortality from cancers of the esophagus, larynx, liver, oropharynx, prostate (male only) and breast (female only).

Results

More restrictive state alcohol policies were associated with lower cancer mortality rates for the six cancer types overall (beta [β] −0.33; 95% confidence interval [CI] −0.59, −0.07), and among men (β −0.45; 95% CI -0.81, −0.10) and women (β −0.21; 95% CI -0.40, −0.02). A 10% increase in the restrictiveness of alcohol policies (based on the mean APS among states) was associated with an 8.5% decrease in rates of combined alcohol-attributable cancers. In all analyses stratified by cancer subtype and sex, the associations were in the hypothesized direction (i.e., more restrictive state policy environments were associated with lower rates of alcohol-attributable cancers), with the exception of laryngeal cancer among women.

Conclusion

Strengthening alcohol policies is a promising prevention strategy for alcohol-related cancer.